Rosacea subtype 1 is easily the most common type of rosacea characterised by reddening skin and thread veins along with other subtypes usually although not always developing progressively. (See rosacea subtypes). Here is a schematic from the change skin tissue following triggering which make the inflammatory response, the harm to capillary structure, the rise in vascular permeability and also the leads to the visible signs and symptoms.
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Underlying chemical processes triggered by Ultra violet for instance are behind these processes whereby various chemicals are freed developing a cascade process leading to reddening and swelling. We show Ultra violet because the trigger here because it is most likely for many the greatest cause of the introduction of signs and symptoms, but other triggers might also lead to initiating the process.
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The schematics contain numerous abbreviations. ROS = reactive oxygen species reely radicals, but free radicals are just an element of the process resulting in damage and losing control from the reddening process. Release and/or inhibition of chemicals triggering irregular tissue growth may underpin phymatous changes (see subtypes) and vascular alterations in circulation system stability, as the early or excessive discharge of cellular chemicals along with the decrease in the discharge or activity of other cellular chemicals can result in a cascade process leading to more rapid and prolonged erythema (reddening and swelling). Types of such chemicals which take part in the procedure are PGE2 (Prostaglandins) and IL1(Interleukin) and Cytokines.
So actually triggers, whether or not they be hormonal, ecological, nutritional or a mix of all, cause dilation of bloodstream vessels, which in susceptible types (genetic type or through excessive acute exposure or exposure with time or a mix of the 3) causes chemical alterations in your skin producing a chemical cascade resulting in erythema as well as in some, cellular and vascular irregularities which could become chronic and severe.
In our opinion, Demodex mites whether folliculorum or brevis might be another physical/chemical trigger factor, and therefore are present in greater levels in rosacea skins as their skin atmosphere is much more favorable on their behalf. But we still believe the primary trigger for many is Ultra violet exposure.
Staying away from triggers from your initial phase is a vital a part of stopping and managing rosacea, but although we can’t change our genetics or hormonal status easily and securely we are able to address many of the reddening process in the above list.
Rosacure® and Synchrorose® (the clinical strength option) continues to be proven to positively target a few of these toxin, enzyme and chemical mediated cascades which are triggered, therefore offering an amount of control regardless of the underlying trigger factors. One must achieve sustained quantity of a ingredients within the skin at an amount whereby they influence the above mentioned processes.
Rosacure® and Synchrorose® (the clinical strength option) continues to be proven to: